One of the great puzzles in science has been the evolution of single-celled organisms into the incredibly wide variety of flora and fauna that we see today. How did Earth make the transition from an initially lifeless ball of rock to one populated only by single-celled organisms to a world teeming with more complex life?
“I’m not recommending anyone taking any drugs. I’m just suggesting we need to have a more scientific rational approach to drugs and vilifying drugs like psilocybin [mushrooms] whilst at the same time actively promoting much more dangerous drugs like alcohol is totally stupid scientifically.”— former UK government drugs adviser Prof David Nutt http://www.bbc.co.uk/news/health-16678322
Consider this: In over five million years of human evolution, only one organ has come to exist for the sole purpose of providing pleasure – the clitoris. It is not required for reproduction. It doesn’t have a urethra running through it like the penis, and thus, does not urinate. Its sole function – its singular, wonderful purpose – is to make a woman feel good!!
With a splitting headache you reach into your medicine cabinet for some aspirin only to find the stamped expiration date on the bottle has passed - two years ago. So, do you take it or don’t you? If you decide to take the aspirin will it be a fatal mistake or will you simply continue to suffer from the headache?
This is a dilemma many people face in some way or another. A column published in Pyschopharmacology Today offers some advice.
It turns out that the expiration date on a drug does stand for something, but probably not what you think it does. Since a law was passed in 1979, drug manufacturers are required to stamp an expiration date on their products. This is the date at which the manufacturer can still guarantee the full potency and safety of the drug.
Most of what is known about drug expiration dates comes from a study conducted by the Food and Drug Administration at the request of the military. With a large and expensive stockpile of drugs, the military faced tossing out and replacing its drugs every few years. What they found from the study is 90% of more than 100 drugs, both prescription and over-the-counter, were perfectly good to use even 15 years after the expiration date.
So the expiration date doesn’t really indicate a point at which the medication is no longer effective or has become unsafe to use. Medical authorities state expired drugs are safe to take, even those that expired years ago. A rare exception to this may be tetracycline, but the report on this is controversial among researchers. It’s true the effectiveness of a drug may decrease over time, but much of the original potency still remains even a decade after the expiration date. Excluding nitroglycerin, insulin, and liquid antibiotics, most medications are as long-lasting as the ones tested by the military. Placing a medication in a cool place, such as a refrigerator, will help a drug remain potent for many years.
Is the expiration date a marketing ploy by drug manufacturers, to keep you restocking your medicine cabinet and their pockets regularly? You can look at it that way. Or you can also look at it this way: The expiration dates are very conservative to ensure you get everything you paid for. And, really, if a drug manufacturer had to do expiration-date testing for longer periods it would slow their ability to bring you new and improved formulations.
The next time you face the drug expiration date dilemma, consider what you’ve learned here. If the expiration date passed a few years ago and it’s important that your drug is absolutely 100% effective, you might want to consider buying a new bottle. And if you have any questions about the safety or effectiveness of any drug, ask your pharmacist. He or she is a great resource when it comes to getting more information about your medications.
Alcohol is more dangerous than illegal drugs like heroin and crack cocaine, according to a new study.
British experts evaluated substances including alcohol, cocaine, heroin, ecstasy and marijuana, ranking them based on how destructive they are to the individual who takes them and to society as a whole.
Researchers analyzed how addictive a drug is and how it harms the human body, in addition to other criteria like environmental damage caused by the drug, its role in breaking up families and its economic costs, such as health care, social services, and prison.
Neuropharmacologist David Nutt, MD, of Imperial College London, and colleagues rated 20 different drugs on a scale that takes into account the various harms caused by a drug. Drugs are rated on nine harms a drug causes an individual and seven harms a drug causes society.
The scale, developed by a panel of experts called the Independent Scientific Committee on Drugs (ICSD), ranges from 0 (no harm) to 100 (greatest possible harm). It is weighted so that a drug that scores 50 is half as harmful as a drug that scores 100.
“The highest and lowest overall harm scores … are 72 for alcohol and 5 for mushrooms,” Nutt and colleagues calculate. “The ICSD scores lend support to the widely accepted view that alcohol is an extremely harmful drug both to users and to society.”
Alcohol was found to be the most harmful drug to society and the fourth most harmful drug to users.
The findings should come as no surprise: Alcohol has been linked to more than 60 diseases.
Whenever you start a project, you should have a plan for finishing it.
One outcome is to declare victory, to find that moment when you have satisfied your objectives and reached a goal.
The other outcome, which feels like a downer but is almost as good, is to declare failure, to realize that you’ve run out of useful string and it’s time to move on. I think the intentional act of declaring becomes an essential moment of learning, a spot in time where you consider inputs and outputs and adjust your strategy for next time.
If you are unable to declare, then you’re going to slog, and instead of starting new projects based on what you’ve learned, you’ll merely end up trapped. I’m not suggesting that you flit. A project might last a decade or a generation, but if it is to be a project, it must have an end.
One of the challenges of an open-ended war or the Occupy movement is that they are projects where failure or victory wasn’t understood at the beginning. While you may be tempted to be situational about this, to know it when you see it, to decide as you go, it’s far more powerful and effective to define victory or failure in advance.
If you can pronounce correctly every word in this poem, you will be speaking English better than 90% of the native English speakers in the world.
After trying the verses, a Frenchman said he’d prefer six months of hard labour to reading six lines aloud.
Dearest creature in creation,
Study English pronunciation.
I will teach you in my verse
Sounds like corpse, corps, horse, and worse.
I will keep you, Suzy, busy,
Make your head with heat grow dizzy.
Tear in eye, your dress will tear.
So shall I! Oh hear my prayer.
Just compare heart, beard, and heard,
Dies and diet, lord and word,
Sword and sward, retain and Britain.
(Mind the latter, how it’s written.)
Now I surely will not plague you
With such words as plaque and ague.
But be careful how you speak:
Say break and steak, but bleak and streak;
Cloven, oven, how and low,
Script, receipt, show, poem, and toe.
Hear me say, devoid of trickery,
Daughter, laughter, and Terpsichore,
Typhoid, measles, topsails, aisles,
Exiles, similes, and reviles;
Scholar, vicar, and cigar,
Solar, mica, war and far;
One, anemone, Balmoral,
Kitchen, lichen, laundry, laurel;
Gertrude, German, wind and mind,
Scene, Melpomene, mankind.
Billet does not rhyme with ballet,
Bouquet, wallet, mallet, chalet.
Blood and flood are not like food,
Nor is mould like should and would.
Viscous, viscount, load and broad,
Toward, to forward, to reward.
And your pronunciation’s OK
When you correctly say croquet,
Rounded, wounded, grieve and sieve,
Friend and fiend, alive and live.
Ivy, privy, famous; clamour
And enamour rhyme with hammer.
River, rival, tomb, bomb, comb,
Doll and roll and some and home.
Stranger does not rhyme with anger,
Neither does devour with clangour.
Souls but foul, haunt but aunt,
Font, front, wont, want, grand, and grant,
Shoes, goes, does. Now first say finger,
And then singer, ginger, linger,
Real, zeal, mauve, gauze, gouge and gauge,
Marriage, foliage, mirage, and age.
Query does not rhyme with very,
Nor does fury sound like bury.
Dost, lost, post and doth, cloth, loth.
Job, nob, bosom, transom, oath.
Though the differences seem little,
We say actual but victual.
Refer does not rhyme with deafer.
Fe0ffer does, and zephyr, heifer.
Mint, pint, senate and sedate;
Dull, bull, and George ate late.
Scenic, Arabic, Pacific,
Science, conscience, scientific.
Liberty, library, heave and heaven,
Rachel, ache, moustache, eleven.
We say hallowed, but allowed,
People, leopard, towed, but vowed.
Mark the differences, moreover,
Between mover, cover, clover;
Leeches, breeches, wise, precise,
Chalice, but police and lice;
Camel, constable, unstable,
Principle, disciple, label.
Petal, panel, and canal,
Wait, surprise, plait, promise, pal.
Worm and storm, chaise, chaos, chair,
Senator, spectator, mayor.
Tour, but our and succour, four.
Gas, alas, and Arkansas.
Sea, idea, Korea, area,
Psalm, Maria, but malaria.
Youth, south, southern, cleanse and clean.
Doctrine, turpentine, marine.
Compare alien with Italian,
Dandelion and battalion.
Sally with ally, yea, ye,
Eye, I, ay, aye, whey, and key.
Say aver, but ever, fever,
Neither, leisure, skein, deceiver.
Heron, granary, canary.
Crevice and device and aerie.
Face, but preface, not efface.
Phlegm, phlegmatic, ass, glass, bass.
Large, but target, gin, give, verging,
Ought, out, joust and scour, scourging.
Ear, but earn and wear and tear
Do not rhyme with here but ere.
Seven is right, but so is even,
Hyphen, roughen, nephew Stephen,
Monkey, donkey, Turk and jerk,
Ask, grasp, wasp, and cork and work.
Pronunciation (think of Psyche!)
Is a paling stout and spikey?
Won’t it make you lose your wits,
Writing groats and saying grits?
It’s a dark abyss or tunnel:
Strewn with stones, stowed, solace, gunwale,
Islington and Isle of Wight,
Housewife, verdict and indict.
Finally, which rhymes with enough,
Though, through, plough, or dough, or cough?
Hiccough has the sound of cup.
My advice is to give up!!!
David Simon, the former Baltimore journalist best known for his HBO series The Wire, was at it again earlier this month, pushing for an end to the War on Drugs in the only way he believes possible: Jury nullification – the process whereby a jury negates a law by acquitting a defendant who is, according to the letter of the law, guilty. That’s the message Simon has spread in the past and that he reiterated to at the Models for Change conference to reform juvenile justice in Washington, D.C. – nullification, he says, is the only way to halt the harm caused by an insatiable drug war machine. In essence, nullification is a way for citizens to send a message to government that a law or particular set of laws are unacceptable. Nullification, Simon reportedly told the conference attendees, is the only way to end the drug war – drug-war prosecutions won’t end, he said at a conference luncheon, won’t end until “they can’t find 12 Americans to put a 13th in jail,” reports Youth Today.